“Thymosin Alpha 1 molecule comes as a add on treatment and a boon for life-threatening sepsis patients,” says Dr Yatin Mehta

India, May 9: Gufic Biosciences Limited (Gufic) has received DCGI approval for Thymosin Alpha-1 (Immunocinα –A Brand of Gufic for the said drug) as an add-on therapy for the treatment of moderate to severe COVID-19 patients requiring ventilator support (NIV as well as Mechanical Ventilation). The pathophysiology and clinical symptoms for Sepsis is the same as for Covid-19.  ThymosinAlpha 1, an Immuno-modulator drug, significantly reduces the risk of death, ventilation days and ICU days, also decreasing hospitalization days as per the various international studies conducted.

Sepsis, a severe and life-threatening complication of an infection, is growing tremendously in India. Today, around one out of two patients admitted in ICU are affected with sepsis across India. The mortality rate/death rate is exceptionally high in severe sepsis patients. Sepsis occurred when chemicals released in the bloodstream to fight an infection trigger inflammation throughout the body. This can cause a cascade of changes that damage multiple organ systems, leading them to fail, sometimes even death. Symptoms include fever, difficulty breathing, low blood pressure, and fast heart rate.

Dr Yatin Mehta, Chairman, Institute of Critical Care & Anaesthesiology, Medanta -The Medicity Hospital, Gurugram, said, “Sepsis is a syndromic response to infection and is frequently a final common pathway to death from many infectious diseases worldwide. A recent scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20% of all global deaths”.

Dr Mehta added, “A study on Indian patients demonstrated that 56.4% of patients admitted in the intensive care unit were suffering from sepsis. In these patients, the most common microorganisms were bacterial (77.9%) followed by fungal (14.1%) infections.”